RNAAgeCalc

This is the development version of RNAAgeCalc; for the stable release version, see RNAAgeCalc.

A multi-tissue transcriptional age calculator


Bioconductor version: Development (3.21)

It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

Author: Xu Ren [aut, cre], Pei Fen Kuan [aut]

Maintainer: Xu Ren <xuren2120 at gmail.com>

Citation (from within R, enter citation("RNAAgeCalc")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("RNAAgeCalc")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews GeneExpression, RNASeq, Software
Version 1.19.0
In Bioconductor since BioC 3.11 (R-4.0) (4.5 years)
License GPL-2
Depends R (>= 3.6)
Imports ggplot2, recount, impute, AnnotationDbi, org.Hs.eg.db, stats, SummarizedExperiment, methods
System Requirements
URL https://github.com/reese3928/RNAAgeCalc
Bug Reports https://github.com/reese3928/RNAAgeCalc/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/RNAAgeCalc
Source Repository (Developer Access) git clone [email protected]:packages/RNAAgeCalc
Package Short Url https://bioconductor.org/packages/RNAAgeCalc/
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